Weak D phenotype is a weakened form of the D antigen which is weakly expressed (70 to 4000 sites). Weak D phenotype is characterized by negative reaction with standard anti-D reagent, that's why it's necessary to perform a specific test in order to detect weak D. Generally, this test is done on pregnant women, newborns and on Rh negative donors to ensure they are truly D negative in order to prevent the formation of anti-D in Rh negative individuals. It may or may not be done routinely on Rh negative candidates for transfusion, depending on the policy of the transfusing institution.
Through its new test featuring EM Technology, DIAGAST provides greater benefits for customers:
Antigens recognition diagram of Qr Anti-D weak clones
Feel free to contact our Product manager Fanny DENIS for further information on this new test.